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Network compression generates broken models when exchange reactions are excluded from compression

Status: Open.

#67 In klamt-lab/straindesign;

· pranasag opened on Jul 12, 2026

Non-deterministic computations when using "BEST" computations despite fixed seed

Status: Open.

Bug

#65 In klamt-lab/straindesign;

· VonAlphaBisZulu opened on Jul 10, 2026

Network compression fails on Yeast-GEM

Status: Open.

Bug

#59 In klamt-lab/straindesign;

· VonAlphaBisZulu opened on Jul 7, 2026

Build the solver backend for Hexaly

Status: Open.

Feature

#46 In klamt-lab/straindesign;

· VonAlphaBisZulu opened on Jun 29, 2026

Gene-level designs contain gene KOs with no reaction-level effect

Status: Open.

Bug

#43 In klamt-lab/straindesign;

· VasilisFlouris opened on Apr 21, 2026

superset-subset solution

Status: Open.

Bug

#38 In klamt-lab/straindesign;

· VasilisFlouris opened on Mar 10, 2026

StrainDesign compatibility issues with enzyme-constrained model

Status: Open.

#18 In klamt-lab/straindesign;

· JakubChromy opened on Dec 13, 2023

Add constraints that are applied to entire nested-optimization approaches

Status: Open.

Feature

#4 In klamt-lab/straindesign;

· VonAlphaBisZulu opened on Aug 15, 2022